Wise Registry Cleaner (portable)

Wise Registry Cleaner Portable is a registry cleaner and optimizer packaged as a portable app, so you can work on PCs on the go. It's freeware for personal and education use. Like many system utilities, this requires admin privileges to run.

Wise Registry Cleaner includes a fast scanner to check for registry problems. It can backup the registry to ensure it is safe to restore. It has the ability to defragment the registry (note that it will require a reboot so ensure all your apps are closed and it will give a warning about not shutting down properly when run again). The interface is very easy to use for novice users and pros alike.

http://portableapps.com/apps/utilities/wise-registry-cleaner-portable

Wise Disk Cleaner (portable)

Wise Disk Cleaner Portable is a disk cleaner and defragmenter packaged as a portable app, so you can work on PCs on the go. It's freeware for personal and education use. Like many system utilities, this requires admin privileges to run.

Wise Disk Cleaner cleans temporary files, history, cookies and autocomplete form history of Internet Explorer, Chrome, Firefox and Safari browsers. And it removes of Windows junk files, such as Recycle Bin, Recent Documents, Temporary files and Log files. This freeware tool cleans a lot more files than most similar products and includes a "slim down" mode that gets rid of a lot of extraneous objects including wallpapers and other Windows files you may never use. A disk defrag feature is also included for free.

http://portableapps.com/apps/utilities/wise-disk-cleaner-portable